Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Encephalopathy
ADR ID BADD_A01462
ADR Hierarchy
17      Nervous system disorders
17.13      Encephalopathies
17.13.02      Encephalopathies NEC
17.13.02.001      Encephalopathy
Description A disorder characterized by a pathologic process involving the brain. [CTCAE] Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM. [MeSH]
MedDRA Code 10014625
MeSH ID D001927
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Encephalopathy | Encephalopathy acute | Encephalopathy chronic | Encephalopathy NOS | Encephalopathy, unspecified | Influenza encephalopathy | Brain Diseases | Brain Disease | Brain Disorders | Brain Disorder | Intracranial CNS Disorders | Central Nervous System Intracranial Disorders | CNS Disorders, Intracranial | CNS Disorder, Intracranial | Intracranial CNS Disorder | Encephalon Diseases | Encephalon Disease | Intracranial Central Nervous System Disorders | Central Nervous System Disorders, Intracranial | Encephalopathies
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Dihydropyrimidine dehydrogenase [NADP(+)]Q12882T75890
Gamma-aminobutyric acid receptor subunit beta-1P15431Not Available
TransketolaseP29401T67754
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00854Etoposide0.002398%
BADD_D00858Everolimus--
BADD_D00865Ezogabine--
BADD_D00869Famotidine0.000262%
BADD_D00871Felbamate--
BADD_D00873Fenofibrate0.000173%
BADD_D00898Finasteride--
BADD_D00914Fludarabine0.000208%
BADD_D00931Fluorouracil0.005645%
BADD_D00932Fluoxetine0.000272%
BADD_D00952Folic acid0.000353%
BADD_D00970Fosphenytoin--
BADD_D00971Fosphenytoin sodium--
BADD_D00979Furosemide0.000285%
BADD_D00981Gabapentin0.000509%
BADD_D00986Gadodiamide hydrate--
BADD_D00998Gallium cation--
BADD_D01000Gallium nitrate--
BADD_D01003Ganciclovir--
BADD_D01004Ganciclovir sodium--
BADD_D01009Gemcitabine0.000695%
BADD_D01016Gentamicin--
BADD_D01024Glipizide0.000118%
BADD_D01030Glyburide0.000415%
BADD_D01033Glycine--
BADD_D01063Hepatitis b vaccine--
BADD_D01064Hepatitis b vaccine (recombinant)--
BADD_D01083Hydrochlorothiazide0.000044%
BADD_D01096Hydromorphone--
BADD_D01119Ibrutinib--
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